Huperzine - A - Uses, Side Effects, and More

Overview

Huperzine A is a chemical that comes from Chinese club moss (Huperzia serrata) or fir club moss (Huperzia selago) plants. It can also be made in a lab.

Huperzine A was identified for medicinal use by scientists at the Chinese Academy of Sciences in the 1980s. It increases levels of a chemical called acetylcholine. This seems to help treat diseases that interfere with memory and thinking.

People use huperzine A to improve memory and mental function in people with Alzheimer disease or other types of dementia. It is also used for depression, schizophrenia, and many other conditions, but there is no good scientific evidence to support these uses.

Don’t confuse huperzine A, which is also called selagine, with similar sounding medications such as selegiline (Eldepryl). Also don’t confuse one of the brand names for huperzine A (Cerebra) with brand names for unrelated prescription drugs such as celecoxib (Celebrex) and citalopram (Celexa).

Huperzine uses

Uses & Effectiveness

Possibly Effective for

  • Alzheimer disease. Taking huperzine A by mouth for up to 6 months might improve memory, thinking skills, and behavior in people with Alzheimer disease.

 

There is interest in using huperzine A for a number of other purposes, but there isn’t enough reliable information to say whether it might be helpful.

When taken by mouth: Huperzine A is possibly safe when taken for less than 6 months. It can cause some side effects including nausea, diarrhea, vomiting, dry mouth, constipation, sweating, and blurred vision.

Special Precautions and Warnings

When taken by mouth: Huperzine A is possibly safe when taken for less than 6 months. It can cause some side effects including nausea, diarrhea, vomiting, dry mouth, constipation, sweating, and blurred vision.

Pregnancy and breast-feeding: There isn’t enough reliable information to know if huperzine A is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Children: Huperzine A is possibly safe in children when taken by mouth for less than one month.

Slow heart rate or other heart diseases: Huperzine A can slow the heart rate. This might be a problem for people who already have a slow heart rate or other heart conditions. If you have heart disease, check with your healthcare provider before using huperzine A.

Seizure disorder (epilepsy): Huperzine A might make epilepsy worse. If you have a seizure disorder such as epilepsy, check with your healthcare provider before using huperzine A.

Gastrointestinal (GI) tract blockage: Huperzine A might make GI blockage worse. If you have a GI tract blockage, check with your healthcare provider before using huperzine A.

Stomach ulcers: Huperzine A might make stomach ulcers worse. If you have stomach ulcers, check with your healthcare provider before using huperzine A.

Lung conditions: Huperzine A might make asthma or chronic obstructive pulmonary disease (COPD) worse. If you have asthma or COPD, check with your healthcare provider before using huperzine A.

Urinary tract blockage: Huperzine A might make blockage of the urinary tract worse. If you have a urinary tract blockage, check with your healthcare provider before using huperzine A.

Past Questions

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